Mouse NewsLett. Gray boxes denote regions where there are no scores for the corresponding test. Conversely, of the 19 high-delta regions that occurred in isolation that is, they were not bordered on either side by another high-delta regiononly 3 produced a top iHS, CLR, or XP-EHH score.
DOC KB. One of the aims of this study was to identify genetic factors that may explain the gender moderation of suicide risk. Actb serves as a positive control for ubiquitous expression and Prm1 as a control for significant expression initiated in round spermatids. GermOnline, a cross-species community knowledge base on germ cell differentiation.
Supplementary information. An independent sample of French-Canadian male subjects was used to assess gene expression. Cell Sci. All the genes represented on the GeneChip were globally normalized and scaled to a signal intensity of Br J Psychiatry ; : — As a consequence, females heterozygous for X-linked coat mutations such as mottled have a variegated coat pattern resulting from the two cell populations, one expressing the mutant allele and the other expressing the wild-type allele Fig.
Zhou E. Tam P. In the mouse, extensive studies of the X-inactivation patterns can be achieved because of the availability of tissues from several replica heterozygotes at a range of times in development on a constant genetic background. SNPs with large allele frequency differences in the other two population comparisons were also commonly found in genes.
Exploring this rationale, candidate gene studies have identified a number of genes with gender-specific effects related to suicidal behaviors, including catechol- O -methyltransferase, 1415 the serotonin transporter 5-HTT16 cholecystokinin 17 and monoamine oxidase A MAO-A. Arch Gen Psychiatry ; 43 : —
We carried out an AMOVA analysis on all X chromosome and autosomal markers using the same population and continental groupings as Ramachandran et al. The female proportion of the effective population size and the female proportion of migration were both varied over a range from 0.
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